Publications

Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Prior, R.L., Cao, G., Martin, A., Taglialatela, G., and Bickford, P.C. Long-term dietary strawberry, spinach or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits. J. Neurosci. 1998. 18: 8047-8055.

Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J. and Bickford, P.C. Reversals of age related declines in neuronal signal transduction, cognitive and motor behavioral deficits with diets supplemented with blueberry, spinach or strawberry dietary supplementation. J. Neurosci. 1999. 19: 8114-8121.

Youdim, K.A., Shukitt-Hale, B., Martin, A., Wang, H., Denisova, N., Bickford, P.C., and Joseph, J.A. Short-term dietary supplementation of blueberry polyphenolics: Beneficial effects on aging brain performance and peripheral tissue function. Nutr. Neurosci. 2000. 3: 383-397.

Joseph, J.A., Arendash, G., Gordon, M., Diamond, D., Shukitt Hale, B., and Morgan, D. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr. Neurosci. 2003. 6: 153-162.

Shukitt-Hale, B., McEwen, J.J., Szprengiel, A., and Joseph, J.A. Effect of age on the radial arm water maze - a test of spatial learning and memory. Neurobiol. Aging. 2004. 25: 223-229.

Joseph, J.A., Shukitt-Hale, B., and Casadesus, G. Reversing the deleterious effects of aging on neuronal communication and behavior: The beneficial properties of fruit polyphenolics. Amer. J. Clin. Nutr. 2005. 81(Suppl.): 313S-316S.

Joseph, J.A., Fisher, D.R. and Carey, A.N. Fruit extracts antagonize AB or DA induced deficits in CA2+ flux in M1 transfected COS 7 cells. J. Alz. Dis. 2004. 6: 403-411.

Casadesus, G., Shukitt-Hale, B., Stellwagen, H.M., Zhu, X., Lee, H-G., Smith, M.A., and Joseph, J.A. Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats. Nutr. Neurosci. 2004. 7, 309-316.

Andres Lacueva, C., Shukitt-Hale, B., Galli, R.L., Jauregui, O., Lamuela-Raventos, R.M., and Joseph, J.A. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutr. Neurosci. 2005. 8: 111-120.

Shukitt-Hale, B., Carey, A., Simon, L., Mark, D.A., and Joseph, J.A. The effects of grape juice on cognitive and motor deficits in aging. Nutrition. 2006. 22: 295-302.

Joseph, J.A., Fisher, D.R., and Bielinski, D. Blueberry extract alters oxidative stress-mediated signaling in COS-7 cells transfected with selectively vulnerable muscarinic receptor subtypes. J. Alz. Dis. 2006. 9: 35-42.

Wilson, M.A., Shukitt-Hale, B., Kalt, W., Ingram, D.K., Joseph, J.A., and Wolkow, C.A. Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans. Aging Cell. 2006. 5: 59-68.

Shukitt-Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph J.A. Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiol. Aging. 2007. 28: 1187-1194.

Joseph, J.A., Fisher, D.R., Carey, A.N., Neuman, A., and Bielinski, D.F. Dopamine-induced stress signaling in COS-7 cells transfected with selectively vulnerable muscarinic receptor subtypes is partially mediated via the i3 loop and antagonized by blueberry extract. J. Alz. Dis. 2006. 10: 423-437.

Lau, F.C., Bielinski, D.F., and Joseph, J.A. Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide-activated BV2 microglia. J. Neurosci. Res. 2007. 85: 1010-1017.