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Current Projects

  • Identifying and quantifying the flavonoid content of: blueberries, cranberries, and grapes; almonds, pistachios, and walnuts; and cocoa-based foods (to contribute to future updates of the USDA Database for the Flavonoid Content of Selected Foods).
  • Determine tissue bioavailability and chemopreventive properties of anthocyanin-rich extracts of blueberries, cranberries, and grapes in animal models.
  • Determining the bioavailability of cranberry anthocyanins and other phenolic compounds in healthy older adults.
  • Determining the effect of almonds (rich in flavonoids and vitamin E) on biomarkers of oxidative stress, inflammation, and vascular reactivity in humans.
  • Determining the effects of walnuts on antioxidant activity and nutritional status in health older adults.
  • Testing whether hibiscus tea (rich in anthocyanins) lowers blood pressure in prehypertensive and mildly hypertensive adults.
  • Investigating in vitro and in vivo the effect of age on quercetin bioavailability and metabolism due to changes in phase II enzyme activity.
  • Testing whether exposure of rat dams to a “Western†diet during pregnancy and lactation will increase obese phenotypes in their pups and whether dietary flavonoids, particularly isoflavones, will decrease the obese phenotype.